The adjuvant activity of serogroup B lipopoly(oligo)saccharide (LOS) from wild-type and genetically-defined LOS mutants and unglycosylated meningococcal lipid A was assessed in C3H/HeN and C3H/HeJ mice. was TLR4-reliant. Unglycosylated meningococcal lipid A because of its weak agonist activity for human macrophages and retention of adjuvant activity may be a candidate for make use of in… Continue reading The adjuvant activity of serogroup B lipopoly(oligo)saccharide (LOS) from wild-type and