Background The biggest sub-unit of RNA polymerase II, Rpb1p, has long been known to be subject to post-translational modifications that influence various aspects of pre-mRNA processing. on simple genetic analysis in yeast model systems C are put forward and discussed. Implications of the Hypothesis These ideas imply that the controlled manipulation of CTD effectors could… Continue reading Background The biggest sub-unit of RNA polymerase II, Rpb1p, has long