The BRCA1 C-terminal (BRCT) domain has recently been implicated as BV-6 a phospho-protein binding domain. data not only implicate BV-6 CtIP as a critical player in cell cycle checkpoint control but also provide molecular mechanisms by which BRCA1 controls multiple cell cycle transitions after DNA damage. DNA damage occurs frequently in the cell. It can… Continue reading The BRCA1 C-terminal (BRCT) domain has recently been implicated as BV-6