Supplementary MaterialsSupplemental Material 41525_2019_79_MOESM1_ESM. that code for the alpha and beta subunits from the platelet membrane adhesive protein receptor complex GPIIb/IIIa (IIb3), respectively.1 Mutations in these genes prevent expression and/or functioning of IIb3 and affect platelet aggregation. A bleeding phenotype results from failure in Itga4 forming platelet aggregates that are required to seal damaged vessel… Continue reading Supplementary MaterialsSupplemental Material 41525_2019_79_MOESM1_ESM. that code for the alpha and beta