The renal collecting duct adapts to changes in acid-base metabolism by remodelling and altering the relative variety of acidity or alkali secreting cells a sensation termed plasticity. A-IC (AE1) and B-IC (pendrin). Induction of remodelling in rats with metabolic acidosis (with NH4Cl for 12 hrs 4 and seven days) or treatment with acetazolamide for 10… Continue reading The renal collecting duct adapts to changes in acid-base metabolism by