The phosphatase Rtr1 has been implicated in dephosphorylation of the RNA Polymerase II (RNAPII) C-terminal domain (CTD) during transcription elongation and in regulation of nuclear import of RNAPII. sequence ‘YSPTSPS’ with increasing numbers of repeats in higher eukaryotes.3-5 Within this sequence it has been well established that the second and fifth serine in the repeats… Continue reading The phosphatase Rtr1 has been implicated in dephosphorylation of the RNA