Engagement of the adhesion receptor glycoprotein (GP) Ib-IX-V by von Willebrand element (VWF) mediates platelet adhesion to damaged vessels and causes platelet activation and thrombus formation in heart attack and stroke. of a stop codon into the pGEX-p85-N vector at nucleotide positions 238, 334, or 904, respectively. Additional constructs were made using pGEX-p85 constructs as… Continue reading Engagement of the adhesion receptor glycoprotein (GP) Ib-IX-V by von Willebrand