Background: A major problem with cisplatin treatment is the development of acquired-drug resistance of the tumour cells. cisplatin-resistant sub-lines (P31res/H1299res) were incubated with VT-1 and/or cisplatin followed by determination of Gb3 expression cell viability apoptosis and signalling pathways. Results: Cells from your resistant sub-lines experienced elevated Gb3 expression compared with the parental cell lines and… Continue reading Background: A major problem with cisplatin treatment is the development of