Objective Autoantibodies against TIF1γ are located in many individuals with dermatomyositis (DM). of histologically regular muscles cells but at high amounts within the centralized nuclei of atrophic perifascicular myofibers expressing markers of regeneration. TIF1γ levels were improved in regenerating myonuclei subsequent muscle injury in mice also. Premature silencing of TIF1γ in vitro using siRNA didn’t… Continue reading Objective Autoantibodies against TIF1γ are located in many individuals with dermatomyositis