In the development of RNA interference (RNAi) therapeutics merely selecting short interfering RNA (siRNA) sequences that are complementary to the messenger RNA (mRNA) target does not guarantee target silencing. only on these two asymmetry guidelines. The algorithm uses end sequence nucleotide preferences and expected thermodynamic stabilities each weighted based on teaching data from your literature… Continue reading In the development of RNA interference (RNAi) therapeutics merely selecting short