Numerous factors donate to the death of substantia nigra (SN) dopamine (DA) neurons in Parkinson’s disease (PD). improved nigrostriatal terminal depletion DA neuron loss the inflammatory response and caspase activation therefore heightening neurodegeneration. The mechanisms underlying this effect are uncertain but the finding that PJ enhanced nitrotyrosine inducible nitric oxide synthase and triggered caspase-3 manifestation… Continue reading Numerous factors donate to the death of substantia nigra (SN) dopamine