Receptor tyrosine kinase signaling is critical for mammalian craniofacial development but the key downstream transcriptional effectors remain unknown. migration during craniofacial development and delineate a mechanism of receptor tyrosine kinase specificity mediated through differential cofactor usage leading to a unique PDGF-responsive SRF-driven transcriptional program in OSI-930 the midface. phenotypes associated with different RTK mutants can… Continue reading Receptor tyrosine kinase signaling is critical for mammalian craniofacial development but