We have demonstrated that Na+/H+ exchanger regulatory factor 1 (NHERF1) overexpression in CFBE41o- cells induces a significant redistribution of F508del cystic fibrosis transmembrane conductance regulator (CFTR) from the cytoplasm to the apical membrane and rescues CFTR-dependent chloride secretion. between ezrin and actin and the overexpression of wt NHERF1 but not NHERF1-ΔERM also increased PK 44… Continue reading We have demonstrated that Na+/H+ exchanger regulatory factor 1 (NHERF1) overexpression