The molecular mechanisms that lead to tubular atrophy capillary loss and fibrosis following acute kidney injury are not very clear but may involve cell cycle inhibition by increased expression of cyclin kinase inhibitors. and levels of p16INK4a apoptosis cell proliferation and capillary rarefaction. KO mice displayed decreased tubular cell apoptosis improved cell proliferation and lower… Continue reading The molecular mechanisms that lead to tubular atrophy capillary loss and