Nuclear receptors (NR) are ligand-modulated transcription elements that play varied tasks in cell differentiation advancement proliferation and rate of metabolism and are connected with several liver pathologies such as for example tumor steatosis inflammation fibrosis cholestasis and xenobiotic/drug-induced liver organ injury. and determining ligands for orphan NR factors to a potential restorative approach for individuals… Continue reading Nuclear receptors (NR) are ligand-modulated transcription elements that play varied tasks
Tag: Posaconazole
tRNA restriction by anticodon nucleases underlies cellular stress responses and self-nonself
tRNA restriction by anticodon nucleases underlies cellular stress responses and self-nonself discrimination in a wide range of taxa. Introduction The yeast secretes a tRNA anticodon nuclease toxin encoded by a resident cytoplasmic linear DNA “killer” plasmid (Satwika et al. 2012 The secreted form of the ribotoxin is a complex of PaOrf1 and PaOrf2 subunits that… Continue reading tRNA restriction by anticodon nucleases underlies cellular stress responses and self-nonself