Background Accumulating evidence suggests that c-kit positive cells are present in the remodeled pulmonary vasculature bed of patients with pulmonary hypertension (PH). (RVH) pulmonary vascular cell proliferation and remodeling were evaluated. Results As compared to chronically hypoxic controls c-kit mutant mice had decreased RVSP RVH pulmonary vascular remodeling and proliferation. Consistent with these findings administration… Continue reading Background Accumulating evidence suggests that c-kit positive cells are present in