The factors that allow self-reactive B cells to escape negative selection and be activated remain poorly described. centers. mice develop raised autoantibody titers in accordance with complement enough controls and present proof glomerulonephritis [20]. Using the anti-hen egg lysozyme (Hel) B-cell Tg model Prodeus et al. [20] reported that insufficiency in C4 potential clients to… Continue reading The factors that allow self-reactive B cells to escape negative selection