Lasonolide A (LSA) is an all natural item with high and selective cytotoxicity against mesenchymal cancer cells including leukemia melanomas and glioblastomas. implicating histone deacetylation as one of the PCC effector mechanisms. In addition PCC is coupled with topoisomerase II (Top2) and Aurora A hyperphosphorylation and activation. Inhibition of Top2 or Aurora A partially blocked… Continue reading Lasonolide A (LSA) is an all natural item with high and