The transcriptional coactivator Yes-associated protein (Yap) promotes proliferation and inhibits apoptosis, suggesting that Yap functions as an oncogene. suppressing apoptosis (Wu et al., 2008; Zhang et al., 2008; Zhao et al., 2008). Yap can be interconnected with RTK (Reddy and Irvine, 2013), GPCR (Yu et al., 2012), PI3E (Lover et al., 2013), Wnt (Bernascone and… Continue reading The transcriptional coactivator Yes-associated protein (Yap) promotes proliferation and inhibits apoptosis,