Receptor tyrosine kinases (RTKs) activate pathways mediated by serine/threonine (Ser/Thr) kinases like the PI3K (phosphatidylinositol 3-kinase)-Akt pathway the Ras-MAPK (mitogen-activated protein kinase)-RSK pathway and the mTOR (mammalian target of rapamycin)-p70 S6 pathway that control important aspects of cell growth proliferation and survival. (EGFR) or platelet-derived growth element receptor a (PDGFRα) RTKs. We recognized a subset… Continue reading Receptor tyrosine kinases (RTKs) activate pathways mediated by serine/threonine (Ser/Thr) kinases