Cytoadherance of Erythrocyte Membrane Proteins 1 (PfEMP1) molecules displayed on the erythrocyte surface are responsible for cytoadherance and undergo antigenic variation in the course of an infection. gene silencing originates within the promoter and PfSir2 paralogues are involved in spreading of silenced chromatin into adjacent regions. Furthermore, parasites lacking PfSir2A but not PfSir2B have considerably… Continue reading Cytoadherance of Erythrocyte Membrane Proteins 1 (PfEMP1) molecules displayed on the