Reduced expression of Paneth cell antimicrobial -defensins, human defensin (HD)-5 and -6, characterizes Crohn’s disease (CD) of the ileum. only and 784 CD patients with ileal involvement were used to determine frequency distributions. We found an association of rs3814570 with ileal CD but neither with colonic CD or UC, in a combined analysis (allele positivity:… Continue reading Reduced expression of Paneth cell antimicrobial -defensins, human defensin (HD)-5 and