Supplementary MaterialsSupplementary Data. is usually a critical target of LKB1/AMPK signals in the regulation of gluconeogenesis. Finally, we show that metformin, one of the most widely prescribed type 2 diabetes therapeutics, requires LKB1 in the liver to lower blood glucose levels. Introduction The adenosine monophosphateCactivated protein kinase (AMPK) is usually a conserved regulator of the… Continue reading Supplementary MaterialsSupplementary Data. is usually a critical target of LKB1/AMPK signals