Oxidative stress-mediated cellular injury has been considered as a major cause of neurodegenerative diseases including Alzheimers and Parkinsons diseases. of p38 and the extracellular signal-regulated kinase (ERK). These results exhibited that CS is usually promising as a potential therapeutic candidate for neurodegenerative diseases resulting from oxidative damage and further research on this topic should be… Continue reading Oxidative stress-mediated cellular injury has been considered as a major cause
Tag: so named for the LIM domains they contain.LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers.
Overexpression of mitochondria-bound hexokinase II (HKII) in tumor cells takes on
Overexpression of mitochondria-bound hexokinase II (HKII) in tumor cells takes on an important part in their metabolic reprogramming and protects them against apoptosis, thereby facilitating their development and expansion. hypoxic circumstances of neoplastic mass accrual (1, 3). Among the 4 isoforms of mammalian hexokinase (HKICHKIV), just HKI and HKII straight interact with mitochondria, both literally… Continue reading Overexpression of mitochondria-bound hexokinase II (HKII) in tumor cells takes on