Supplementary MaterialsSupplementary Information 41467_2019_8957_MOESM1_ESM. and inactivates the spindle assembly checkpoint (SAC). Cdk1 phosphorylates DIAPH1, avoiding profilin1 binding to keep up cortical pressure. Mutation of DIAPH1 phosphorylation sites promotes cortical F-actin build up, increases cortical pressure, and delays anaphase onset due to SAC activation. Measurement of the intra-kinetochore size suggests that Cdk1-mediated cortex relaxation is definitely… Continue reading Supplementary MaterialsSupplementary Information 41467_2019_8957_MOESM1_ESM. and inactivates the spindle assembly checkpoint (SAC).