Background A limitation of current antiplatelet therapies is their inability to separate thrombotic events from bleeding occurrences. This phosphatase is usually highly expressed in human and mouse platelets. Platelets from DUSP3-deficient mice displayed a selective impairment of aggregation and granule secretion mediated through the collagen receptor glycoprotein VI (GPVI) and the C-type lectin-like receptor 2… Continue reading Background A limitation of current antiplatelet therapies is their inability to