Background Allogeneic tolerance could be reliably obtained with monoclonal antibody therapy targeting CD45RB. transfer of control splenocytes to B-cell-deficient recipients permitted anti-CD45RB-induced tolerance, whereas transfer of ICAM?/? cells was unable to support tolerance induction. Conclusions Manifestation of ICAM-1 by B lymphocytes and connection with LFA-1 form a central aspect of transplantation tolerance induced by anti-CD45RB… Continue reading Background Allogeneic tolerance could be reliably obtained with monoclonal antibody therapy