The mature protease from Group N human immunodeficiency virus Type 1 (HIV-1) (PR1N) differs in 20 proteins in the extensively studied Group M protease (PR1M) at positions corresponding to small drug-resistance mutations (DRMs). affinities for DRV and two various other clinical PIs, recommending that minimal DRMs coevolve to pay for the harmful ramifications of drug-specific… Continue reading The mature protease from Group N human immunodeficiency virus Type 1