The cohesin complex is essential for mitosis and meiosis. distributed throughout the chromatin and SYCP1 which normally marks synapsed axes is largely absent. Centromeric and telomeric sister chromatid cohesion are impaired. Centromere and telomere clustering happens in the absence of STAG3 and telomere structure is not seriously affected. Additional cohesin proteins are present localize throughout… Continue reading The cohesin complex is essential for mitosis and meiosis. distributed throughout