Mutations in bring about heterotaxy or isolated congenital cardiovascular disease (CHD). practical analyses included 4 extra reported but untested variations. Aberrant cytoplasmic localization and reduced luciferase transactivation had been observed for many zinc-finger variations however not for downstream or in-frame upstream variations including Rabbit polyclonal to CTGF. both examined polyalanine expansions. Collectively these outcomes increase… Continue reading Mutations in bring about heterotaxy or isolated congenital cardiovascular disease (CHD).