An endogenous metabolite of 17-estradiol, 2-methoxyestradiol (2-ME), has affinity for estrogen receptors. cell death induced by the upregulation of phosphorylated extracellular-signal-regulated kinase 1/2 signaling pathway. The results of the present study exhibited that 2-ME, which is usually used as a therapeutic agent for treating solid tumors, exhibits apoptotic and anti-proliferative effects depending on the dose.… Continue reading An endogenous metabolite of 17-estradiol, 2-methoxyestradiol (2-ME), has affinity for estrogen
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Congenital Dyserythropoietic Anemia type II can be an autosomal recessive disorder
Congenital Dyserythropoietic Anemia type II can be an autosomal recessive disorder seen as a exclusive abnormalities in the differentiation of cells from the erythroid lineage. is normally considerably higher in Italy (26.3% vs. 10.7%). By haplotype evaluation we showed that both are creator mutations in the Italian people. Utilizing the DMLE+ plan our estimation for… Continue reading Congenital Dyserythropoietic Anemia type II can be an autosomal recessive disorder