Angiogenesis is regulated by coordinated actions of varied protein with pro- and anti-angiogenic features highly. of c-Cbl also led to solid activation of PLCγ1 and elevated intracellular calcium discharge. c-Cbl-dependent ubiquitination selectively inhibited tyrosine phosphorylation of PLCγ1 and refrain it from ubiquitin-mediated degradation mostly. Therefore we propose c-Cbl as an angiogenic suppressor proteins where upon… Continue reading Angiogenesis is regulated by coordinated actions of varied protein with pro-